In cases with chronic atopic dermatitis, BIOPTRON® Hyperlight therapy can decrease the need of other treatments. The mechanisms of BIOPTRON® Hyperlight Therapy in the treatment of eczema are:

• BIOPTRON® Hyperlight increases the mobility and migration of fibroblasts:
  In every dermatological disorder, the regeneration of the skin is a pivotal process. BIOPTRON® Hyperlight increases the mobility of newly-formed fibroblasts, a critical process to skin healing. BIOPTRON® Hyperlight promotes the expression of binding factors that promote this migration, contributing actively to faster regeneration of the damaged skin (unpublished data).
• BIOPTRON® Hyperlight increases collagen production:
  Collagen is an essential protein for the entire body. Collagen is the skin’s support, providing it with the firmness and elasticity it needs to move and function healthily. BIOPTRON® Hyperlight increases the production of endogen collagen, giving skin the structure and stability it needs. BIOPTRON® Hyperlight therapy fosters the recovery of the skin to a healthy and functional state (De Melo et al., 2016).
• BIOPTRON® Hyperlight improves microcirculation:
  Capillaries (the smallest blood vessels) are responsible for the supply of oxygen and nutrients to our tissues and cells, as well as for the removal of toxic substances. BIOPTRON® Hyperlight increases the blood flow in irradiated capillaries, boosting the oxygen and nutrients supply, as well as the uptake of nocive substances produced by damaged cells. BIOPTRON® Hyperlight Therapy provides to the newly-formed cells all they need to favour a healthy skin regeneration (Samoilova et al., 2008).
• BIOPTRON® Hyperlight promotes angiogenesis:
  Damaged tissues are very often characterized by poor and deficient blood supply, which could slow down and delay the recovery. BIOPTRON® Hyperlight promotes angiogenesis, developing new capillaries. The increased number and length of capillaries contribute to healthy tissue regeneration and shorter recovery time (Gasparyan et al., 2010).
• BIOPTRON® Hyperlight eliminates superficial bacterial infections:
  Some dermatological problems are caused by bacteria, in other cases bacteria are the factor that worsened the skin problem. BIOPTRON® Hyperlight contains blue light, very well known for its intrinsic antimicrobial effect without the addition of exogenous photosensitizers. BIOPTRON® Hyperlight prevents the development of bacterial infection that can provoke and reinforce dermatological disorders (Opel et al., 2015).
• BIOPTRON® Hyperlight diminishes the inflammation:
  Inflammation is a common side-effect in some dermatological indications that can deteriorate tissue condition. BIOPTRON® Hyperlight decreases the production of pro-inflammatory cytokines, such as IL-6 and TNF-a, by lymphocytes in the irradiated region, reducing locally the inflammation of the affected epithelium (Falus et al., 2011).